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About Lady Wolf Moon
Before Patrick Mahomes laced up his cleats for his 2026-2027 NFL regular-season debut, US prediction markets had already cleared a historic benchmark for the opening week of the season.
Two operators alone – Kalshi and Polymarket – topped the combined $1 billion mark in NFL trading activity over the first six days of Week 1, according to numerous measures this week. During the period, Kalshi recorded NFL volume of $983.4 million, according to DeFi Rate, earning the pole position by a large margin. Mahomes and the Kansas City Chiefs thrashed the Denver Broncos 31-10 on Monday Night Football, capping the largest week for prediction markets ever.
Even before the primetime matchup in Kansas City, it became abundantly clear that the industry would shatter previous marks for weekly activity. The AFC West showdown bolstered the already robust totals. Overall, volume for the week hit a record $15.9 billion, according to Bank of America, up 16% from a week earlier.
How to play Lady Wolf Moon
During his tenure, Rodano was instrumental in deploying an AI-powered behavioural analytics platform, BetBuddy, which is designed to identify and intervene in potentially harmful gambling behaviours.
Before moving to the private sector, Rodano served as the director of remote gaming at Italy’s regulator, Agenzia Dogane e Monopoli, for almost a decade.
He played a significant part in establishing Italy’s national online gaming framework and liaised with international regulatory bodies.
What is Lady Wolf Moon?
The Polymarket ad campaign debuted less than 48 hours before Wednesday’s NFL regular-season opener. The matchup is a rematch of last season’s Super Bowl as the Seattle Seahawks host the AFC Champion New England Patriots.
Last February in Santa Clara, the Seahawks held the Patriots scoreless through three quarters en route to a 29-13 win. That said, the defending champions are not the favourites to win the Lombardi Trophy this year. Nearly every US operator has installed the Los Angeles Rams as the overwhelming choice to capture the title.
As of 6pm ET, the Seahawks had a 62% probability on Polymarket to defeat the Patriots in Wednesday’s opener. Conversely, Polymarket traders gave the Patriots a 39% chance to pull the upset. At those odds, a $100 contract on the Pats carries a payout of $247.35.
